Airway inflammation: Like classical asthma, CVA is believed to involve inflammation and hypersensitivity of the airways. This inflammation can be triggered by various factors.

Allergens: Exposure to allergens such as pollen, dust mites, pet dander, mold, and certain foods can trigger asthma symptoms, including coughing.

Respiratory infections: Viral respiratory infections, such as the common cold or flu, can trigger coughing in individuals with cough variant asthma. Infections may also exacerbate underlying airway inflammation.

Exercise: Physical activity, particularly in cold or dry air, can trigger coughing in individuals with cough variant asthma. This is known as exercise-induced asthma.

Environmental irritants: Exposure to irritants such as smoke, strong odors, pollution, and airborne chemicals can trigger coughing in people with CVA.

Cold air or changes in weather: Cold air can trigger asthma symptoms, including coughing. Additionally, changes in weather patterns, such as fluctuations in temperature or humidity, may also trigger cough variant asthma symptoms.

Gastroesophageal reflux disease (GERD): Some individuals with CVA may also have underlying GERD, where stomach acid refluxes into the esophagus. Acid reflux can irritate the airways and trigger coughing.

Stress: Emotional stress or anxiety can sometimes trigger asthma symptoms, including coughing.